- More good news for tropical disease research!
New active compounds against Malaria from the GSK libraries
GlaxoSmithKline (GSK) screened nearly 2 million compounds from their chemical library for inhibitors of P. falciparum, of which 13,533 were confirmed to inhibit parasite growth by at least 80% at 2 mM concentration. More than 8,000 also showed potent activity against the multidrug resistant strain Dd2. Chemical [...]
- Open Science discussed in Chemistry in Australia
Open Science discussed in Chemistry in Australia
Our friend Matthew Todd talks about Open Science in general in this Q & A in the Chemistry in Australia Journal. You can read more here.
- TDI featured in Tropika.net
TDI featured in Tropika.net
Tatum Anderson has written a nice piece on Open Source Drug Discovery. She has covered and compared our TDI efforts within a more general OSDD approach. You can read more here.
- Good news for Tropical Disease Research!
New collaboration between Pfizer and DNDi.
Pfizer Inc and Drugs for Neglected Diseases initiative (DNDi) have signed an agreement that is designed to facilitate advancements in the battle against human African trypanosomiasis (HAT), visceral leishmaniasis (VL) and Chagas disease, which afflict vulnerable populations in the developing world. Under the agreement, DNDi will have access [...]
- TDI presented at Duke-NUS (Singapore)
July 16th, 2009
TDI was presented at the DUKE-NUS University in Singapore. Slides can be found here.
- Blogging about TDI’s kernel start appearing…
Common Knowledge blog post
We are glad to see that our kernel is starting to spark some comments and posts in the blogsphere. For example, John Wilbanks, who runs the Science Commons project at Creative Commons, has some nice thoughts on our approach.
- More on our TDI kernel. Now in PLoS NTD!
PLoS Neglected Tropical Diseases published with full details our kernel.
The detailed description on how our The Tropical Disease Initiative kernel was produced have been published in the last issue of the PLoS Neglected Tropical Diseases journal. You can read about it in the PLoS NTD site at this link. For fair use, you can download the PDF here.
Marc A. [...]
- Our TDI kernel has been published!
Nature Biotech published our kernel.
The Tropical Disease Initiative kernel has been published in the last issue of the Nature Biotechnology journal as a correspondence to the Editor. You can read about it in the NatBioTech site at this link. The whole kernel will be published soon in the PLoS Neglected Tropical Diseases journal. We’ll keep [...]
- Open Source Drug Discovery. A feasible business model?
Open Source Drug Discovery. A feasible business model?
Jagadeesh Napa (Assistant Editor of Pharma Focus Asia) has a nice assay on Open Source Drug Discovery and is feasibility as a business model. We are glad that Jagadeesh has named TDI as one of the “major open source initiatives”.
- 2008 Target Competition for Neglected Diseases (UC Berkeley)
2008 Target Competition for Neglected Diseases (UC Berkeley)
As part of their upcoming symposium, Infection & Host Response (Dec. 12, 2008 at UC Berkeley, http://cend.berkeley.edu), the UC Berkeley Center for Emerging and Neglected Diseases is sponsoring a Target Competition in which the winner will receive a screen of up to 100,000 molecules in the QB3 Small Molecule Discovery Center (SMDC).
